Flavonoids Can Protect Maize DNA from the Induction of Ultraviolet Radiation Damage

Flavonoids can protect maize DNA from the induction of ultraviolet radiation damage.

Diverse flavonoid compounds are widely distributed in angiosperm families. Flavonoids absorb radiation in the ultraviolet (UV) region of the spectrum, and it has been proposed that these compounds function as UV filters. We demonstrate that the DNA in Zea mays plants that contain flavonoids (primarily anthocyanins) is protected from the induction of damage caused by UV radiation relative to the...

Ultraviolet Radiation Damage in DNA

Introduction The evolution of most forms of life has occurred in an environment exposed to the ultraviolet (UV) and visible radiation emanating from the sun. When molecules in living cells absorb photons in this region of the electromagnetic spectrum they are promoted to excited electronic states and this process can have profound biological consequences. In general, visible wavelengths (400-78...

Radiation track and DNA damage

The green tea polyphenol (-)-epigallocatechin gallate and green tea can protect human cellular DNA from ultraviolet and visible radiation-induced damage.

BACKGROUND Antioxidant compounds in green tea may be able to protect against skin carcinogenesis and it is of interest to investigate the mechanisms involved. A study was therefore conducted to determine whether the isolated green tea polyphenol (-)-epigallocatechin gallate (EGCG) could prevent ultraviolet radiation (UVR)-induced DNA damage in cultured human cells. This work was then extended t...

Molecular Mechanisms of Ultraviolet Radiation-Induced DNA Damage and Repair

DNA is one of the prime molecules, and its stability is of utmost importance for proper functioning and existence of all living systems. Genotoxic chemicals and radiations exert adverse effects on genome stability. Ultraviolet radiation (UVR) (mainly UV-B: 280-315 nm) is one of the powerful agents that can alter the normal state of life by inducing a variety of mutagenic and cytotoxic DNA lesio...